A number of urinary proteins have been proposed as biomarkers of kidney damage in kidney disease progression, such as uromodulin (Prajczer et al., 2010), kidney injury marker 1 (KIM1) (van Timmeren et al., 2007), and neutrophil gelatinase-associated lipocalin (NGAL) (Viau et al., 2010). The gene discussed is LCN2; the disease is Nephropathy.