CRP and major depressive disorder: Our phenotypic analyses revealed no association between CRP and MDD but did suggest a strong effect of BMI and reported trauma on both CRP (BMI: β = 0.43, 95% CI = 0.43–0.43, p ≤ .001; childhood trauma: β = 0.02, 95% CI = 0.00–0.03, p = .006) and MDD (BMI: odds ratio [OR] = 1.16, 95% CI = 1.14–1.19, p ≤ .001; childhood trauma: OR = 1.99, 95% CI = 1.88–2.11, p ≤ .001).