AKT1 and renal carcinoma: Renal Cancer; stimulate apoptosis in Caki cells via DNA fragmentation, the activation of cas-pase-3, cleavage of phospholipase C-g1, and the stimulation of ROS generation by the production of cytochrome c and downregulation of the Bcl2, Bcl-xL, IAP, and Akt pathways.