NGF was experimentally proved to inhibit NGF decreasing neuroma formation, and minimizing neuropathic pain in traumatic neuroma formation after peripheral nerve injury (14), by applying an antibody against a specific receptor (trkA), or antibody against brain-derived neurotrophic factor (BDNF) which is usually upregulated after nerve injury by NGF (56). The gene discussed is NGF; the disease is peripheral nerve injury.