Importantly, ERCC1 expression levels in peripheral blood only relatively reflect the repair situation of patients with ischemic stroke to a certain extent, and future studies are needed to detect ERCC1 expression in atherosclerotic plaque or edema area, ischemic penumbra, or ischemic core in ischemic stroke animal models and clarify the detailed function of the ERCC1 gene in the pathophysiology of ischemic stroke. Here, ERCC1 is linked to ischemic stroke.