As high c-MYC levels are detected often in TNBC (27) and we recently demonstrated that n-MYC, a closely related paralog of c-MYC, sensitizes cancer cells to NOXA-mediated toxicity (28), we asked whether c-MYC expression could be a potential factor in TAK-243 efficacy in TNBC. The gene discussed is MYC; the disease is cancer.