Independent indicators of AF/AFL induced TCM were age<79 years [Odds ratio 5.887, confidence interval (CI) 1.999–17.339, p < 0.001], NT-pro-BNP <5,419 pg/mL (Odds ratio 2.327, CI 1.141–4.746, p = 0.004), and a resting heart rate >112 bpm (Odds ratio 2.503, CI 1.288–4.864, p = 0.001). The gene discussed is NPPB; the disease is atrial fibrillation.