When entered into separate models, baseline GLS and LVEF were both significantly associated with the endpoint, independently of age, sex, baseline NT-proBNP and the duration of HF (Table 3), with HRs(95%CI) per SD change of 2.15(1.34–3.46) and 1.41(1.01–2.13), respectively. Here, NPPB is linked to hydrops fetalis.