Compared to the healthy control, 13 genes down-regulated (SERPINA3, PLA2G2A, IL1RL1, CD163, SERPINE1, FCN3, CYP4B1, LYVE1, S100A8, SLCO4A1, MYOT, ANKRD2, and VSIG4) and 7 genes up-regulated (MXRA5, FRZB, HBB, LUM, SFRP4, NPPA, and ASPN) in the DCM individuals (Figure 2). The gene discussed is S100A8; the disease is familial dilated cardiomyopathy.