Similarly, the hypothetical protein bbk15 on the mammalian infection-essential replicon lp36 (Jewett et al., 2007), has a predicted 5′ derived sRNA (SR0821) within its 5′ UTR with a Rho termination region directly downstream the 5′ UTR 3′ end (Figure 3E). The gene discussed is RHO; the disease is infection.