TP53 and acute myeloid leukemia: In addition to the differences in relative telomere content, insertions of telomeric repeats into intrachromosomal regions (example shown in Figure 6D; Supplementary Table 11) were detected in 13/42 (31%) TP53-mutated AML/MDS tumor samples but none of the CBF tumor samples (p=0.0061, Fisher’s exact test; Figure 6E).