In TP53-mutated AML/MDS samples, we observed a median of 71 somatic SVs per sample ( range: 2–576, Figure 4A, Supplementary Table 4), which were classified as follows: deletion (DEL), duplication (DUP), insertion (INS), inversion (INV), and break-end (BND). This evidence concerns the gene TP53 and myelodysplastic syndrome.