Also, given that mTORC1 and ODC inhibition blunted refeeding stimulated protein translation in intestinal progenitors (Fig. 4h, i), we treated refed Apcloxp/loxp: Villin-CreERT2 mice with cycloheximide, an inhibitor of eukaryotic translation or protein synthesis, to ascertain whether dampening elevated protein translation in the refed state impacted intestinal tumour formation (Fig. 6e). The gene discussed is ODC1; the disease is neoplasm.