The abundance of Prevotella histicola in the EAE mice with OMAT treatment was also significantly increased from 0.013% to 1.44%, which was reported could down-regulate the pro-inflammatory Th1/Th17 response and induce regulatory CD4+FoxP3+ regulatory T cells (Treg) to inhibit the occurrence of MS (Mangalam et al., 2017; Blais et al., 2021). The gene discussed is FOXP3; the disease is myeloid sarcoma.