But the family Erysipelotrichaceae showed a tendency to increase with age in transgenic mice, and this bacterial family appears to be very immunogenic and highly coated by IgA in the gut (Palm Noah et al., 2014), it is abundant in inflammatory bowel disease (Schaubeck et al., 2016) and colorectal cancer (Chen et al., 2012). Here, CD79A is linked to inflammatory bowel disease.