These genes occur within the same 17p13.3 chromosomal region as the Lis1 gene (PAFAH1B1) that is frequently subject to microdeletion or microduplication events causative for the neurodevelopmental disorder Miller-Dieker Syndrome, in which patients exhibit severe lissencephaly (Cardoso et al., 2003; Toyo-oka et al., 2003; Yingling et al., 2003). This evidence concerns the gene PAFAH1B1 and Miller-Dieker lissencephaly syndrome.