Genomic profiling of small RNA levels in response to ML-60218 in THP-1, an acute myeloid leukemia cell line, identifies a specific subrepertoire of Pol III-transcribed genes that are significantly reduced in response to drug exposure, including snaR ncRNA and other putatively POLR3G-sensitive small ncRNAs, whereas most Pol III-transcribed genes are insensitive (Van Bortle et al., 2022). This evidence concerns the gene POLR3G and acute myeloid leukemia.