Strikingly, ob-dT bASCs already displayed an enhanced gene expression of CXCL2, CXCL1, CXCL3, FGF2 and CCL2, compared to ln-dT bASCs (Fig. 4A), suggesting a crucial impact of obesity on bASCs. The gene discussed is CXCL2; the disease is obesity due to melanocortin 4 receptor deficiency.