KRT10 and psoriasis: Keratin 10(KRT10) is a keratin marker produced in well-differentiated upper basal keratinocytes and was reported to be significantly decreased in lesions of psoriasis.28,29 We detected the mRNA expression of KRT10 and found that the expression of KRT10 was significantly decreased in the ears of Co-2M mice and 6 M mice compared with Sep-2M (Supplementary Fig. 2f).