This result is also consistent with the research result of Hesuiyuan Wang and his colleagues who demonstrated that Parabacteroides distasonis was significantly increased after administration of gentamicin.37 In general, administration of gentamicin alleviated the pathogenesis of psoriasis-like skin phenotype in K14-VEGF mice by reducing the abundance of Prevotella and increasing the abundance of Parabacteroides distasonis. The gene discussed is KRT14; the disease is psoriasis.