Glutathione S‐transferases (GSTs), a super‐enzyme family including at least eight classes of isoenzymes, mediate strong cytoprotective capacities by eliminating toxic substances such as xenobiotics, carcinogens, and electrophiles through catalytic conjugation to glutathione.[6] Intracellular glutathione metabolism has both beneficial and pathogenic impacts on several types of cancers. Here, HPGDS is linked to cancer.