Analysis of 15 GST isoforms of human lung cancer using the TCGA dataset showed GSTP1, GSTA2, GSTA5, GSTO2, and GSTZ1 were significantly upregulated in LUAD compared to corresponding normal tissues, suggesting their potential oncogenic effects on LUAD (Figure 6A; Figure S8, Supporting Information). This evidence concerns the gene GSTZ1 and lung cancer.