This result is also consistent with the findings that overexpression of KEAP1 completely suppressed the expression of GSTA1 instead of GSTP1 in Caco‐2 colorectal adenocarcinoma cells.[34] Together, results from current study indicated that the CaMK2A/NRF2/GSTP1 comprises a functional axis in CSC regulation. Here, KEAP1 is linked to colorectal adenocarcinoma.