These outcomes suggest that the tumor suppressor effect of ANXA10 is related to m6A; ANXA10 may regulate HNRNPA2B1, IGF2BP3, METTL3, RBM15, YTHDF1 and YTHDF2 to affect the methylation level of LIHC (Supplementary Information). This evidence concerns the gene METTL3 and neoplasm.