CDK2 and glioblastoma: However, to what extent the expression and phosphorylation levels of CDK1 and CDK2 are impacted by the cell cycle in glioblastoma cells is unknown and especially for pCDK1/pCDK2 we observed a higher increase of 3.8 and 3.2-fold in BS153vIII+ cells, which can hardly be explained by the increase in S/G2 phase cells alone (Figs. 1B, C, 3A).