大部分属常染色体隐性遗传,少数(FANCB亚型)为X连锁遗传;主要表现为血细胞减少、先天畸形、幼年癌症,染色体断裂试验阳性,易进展为MDS/AML. The gene discussed is FANCB; the disease is acute myeloid leukemia.