患者一般临床特征:100例伴有MLL-r融合基因的AML患者根据MLL-r的种类分为四组:MLL-AF9(35例),MLL-AF10(19例),MLL-AF6(27例)和其他MLL-r(19例,其中1例AF17,2例AF1q,2例AF4,11例MLL-ELL,1例MLL-ENL,2例MLL-SEPT9)。四组患者的临床资料见表1。各组伴MLL-r的AML患者主要分布在M4、M5两个亚型中。. This evidence concerns the gene KMT2A and acute myeloid leukemia.