EP300 and B-cell non-Hodgkin lymphoma: Also, the relation of p300 and c-Myc has been reported in 293T, osteosarcoma, and B-cell lymphoma cell lines, indicating that p300 can bind to c-Myc and regulate its stability (46, 47, 48), whereas p300 showed limited effect on c-Myc expression in NB cell lines based on our results.