LPA and diabetes mellitus: Our meta-analysis indicated an association of Lp(a) with higher risk of CVD-death in general population (HR: 1.33, 95%CI: 1.11–1.58, I2: 82.8%, n = 31, Supplementary Figure-3), patients with CVD (HR: 1.25, 95%CI: 1.10–1.43, I2: 54.3%, n = 17, Supplementary Figure-4) and patients with DM (HR: 2.53, 95%CI: 1.13–5.64, I2: 66%, n = 4).