MAPT and Alzheimer disease: Interestingly, we did not observe a significant decrease in the levels of phospho‐tau Thr181 [Hippocampus: P(AD) = 0.0517; Cortex: P(AD) = 0.1791], Ser202 [Hippocampus: P(AD) = 0.3984; Cortex: P(AD) = 0.4635], or Ser396 [Hippocampus: P(AD) = 0.0623; Cortex: P(AD) = 0.9968] in the AD mice treated with apicidin (Figure 6B–H).