HK2 and central nervous system cancer: In addition, western blot analysis showed that HK2 expression was significantly upregulated in in‐miR‐143‐3p‐treated U87, T98, and GBM1 glioma cells (Fig. 5G), implying that miR‐143‐3p could regulate HK2 expression by targeting the 3'UTR of the HK2 gene in glioma.