While inflammasome‐associated IL‐1β secretion by tumor‐associated macrophages and cancer‐associated fibroblasts may promote tumor growth and metastasis by suppressing antitumor immunity [42, 43, 44], inflammasome activation also enhances antitumor activity of CD8+ T cells and NK cells through IL‐18, promotes tumor infiltration of lymphocytes, and strengthens the response to checkpoint inhibitors [45, 46, 47, 48]. The gene discussed is IL18; the disease is cancer.