At 3 h post infection the IL-21 level was 95% which decreased significantly at 6 h (74%, p < 0.0038), 12 h (55%, p < 0.0005) and finally decreased to the level 37% (p < 0.0001) at 24 h post infection (Fig. 5) when compared to the level expressed at 0 h post JEV infection. Here, IL21 is linked to infection.