In the clone formation experiment (Fig. 6C), the formation rate of breast cancer cells in the sh-CYP1A1 group decreased compared with the vehicle and size of breast cancer cell clones in the sh-CYP1A1 group were lower than those in the vehicle group, and the formation ability of breast cancer cell clones in the THC + sh-CYP1A1 group was lower than that in the high-dose THC group. The gene discussed is CYP1A1; the disease is breast cancer.