If active extravasation is noted on CT in at least secondary branches of the renal vessels, depending on the patient’s hemodynamics, severity of injury, need for ongoing blood product transfusions, presence of other injuries, availability of in house surgical team, ICU availability, pre-existing renal failure and contrast load on initial scan, patients may undergo angioembolization, or be closely monitored hemodynamically with serial hemoglobin (Hb) assessments and serial creatinine (Cr) and urine output measurements. The gene discussed is GSTM1; the disease is kidney failure.