According to the scores of degree, closeness centrality, betweenness centrality, and clustering centrality, signal transducer and activator of transcription 3 (STAT3), heat shock protein HSP 90-alpha (HSP90AA1), vascular endothelial growth factor A (VEGFA), fibroblast growth factor-2 (FGF2), and interleukin-2 (IL-2) were identified as the top 5 intersecting targets of Aspiletreins and NSCLC interaction (Fig. 4C and Table S2). The gene discussed is VEGFA; the disease is non-small cell lung carcinoma.