BRCA1 and ovarian cancer: Though we performed tests at the levels of individual genes, we did not find any significant (p ≤ 0.05), replicable associations beyond the well-known association of BRCA1 (discovery cohort: OR = 2.91; p-value = 1.14e-04; 95% CI: 1.67–5.32, validation cohort: OR = 2.91; p-value = 1.06e-03; 95% CI: 1.55–5.35) and BRCA2 (discovery cohort: OR = 3.04; p-value = 9.35e-04; 95% CI: 1.55–6.46, validation cohort: OR = 2.50; p-value = 1.04e-03; 95% CI: 1.46–4.18) with breast and ovarian cancer risk (Supplementary Data 1).