TNC and central nervous system cancer: We further examined the expression of three NRF2 putative target genes whose encoded proteins are associated with senescence, glioma progression or glioma resistance, respectively, namely urokinase plasminogen activator receptor (uPAR) encoded by Plaur49, Tenascin-C (TNC)50 or Connexin43 (CX43) encoded by Gja1)51.