We further examined the expression of three NRF2 putative target genes whose encoded proteins are associated with senescence, glioma progression or glioma resistance, respectively, namely urokinase plasminogen activator receptor (uPAR) encoded by Plaur49, Tenascin-C (TNC)50 or Connexin43 (CX43) encoded by Gja1)51. This evidence concerns the gene NFE2L2 and central nervous system cancer.