In a stratified analysis, participants who were concurrently receiving both ginseng and conventional cancer treatment (conventional cancer treatment n = 83; tamoxifen n = 23; aromatase inhibitor n = 27; antiandrogen n = 2) demonstrated a statistically significant improvement in fatigue score at both week 4 and 8 compared to placebo group (n = 83) [81]. This evidence concerns the gene CYP19A1 and cancer.