ERN1 and COVID-19: Comparison between 2806 COVID-19 patients above the age of 30 and 532,493 recent unique hospital patient records showed a significant over-representation of patients taking thiazolidinediones, metformin, SGLT2 inhibitors, statins, or telmisartan (IRE1α inhibitor) across all COVID-19 severity indicators (Figure 4; Figure 4—figure supplement 1; Supplementary file 2).