In addition, with the discovery of the relationship between osteoarthritis and IL‐1β‐induced chondrocyte apoptosis,4 there is increasing evidence that IL‐1β can induce apoptosis, such as cardiomyocyte,5 nucleus pulposus cells,6 human umbilical vein endothelial cells,7 β‐cells,8 and fibrosus cells.9 This evidence concerns the gene IL1B and osteoarthritis.