At the single nucleotide polymorphism (SNP) mutation level and transcriptional level, we found that MAP4, YWHAG, KSR2, SPAG9, and CEP250 gene-related loci are different in cancer and paracancer tissues, and MAP4, YWHAG, CEP135, and CEP250 differed significantly at the transcriptional level (Fig. 7). This evidence concerns the gene KSR2 and cancer.