YWHAG was mainly involved in the regulation of mitosis and the signal transduction between cells and other biological processes, and was closely related to tumor migration and proliferation.[32] Wang et al found that the upregulation of YWHAG could inhibit the viability, proliferation, migration, invasion, and mitosis of glioblastoma.[33] Chu et al found that miR-222 could inhibit the proliferation and invasion of osteosarcoma cells by downregulating the expression of YWHAG.[34]. The gene discussed is YWHAG; the disease is osteosarcoma.