S100A13 and age-related macular degeneration: Additionally, protein S100-A13 was significantly related to early AMD risk in both IVW (OR = 1.07, p-value = 1.22E−05) and other measures (weighted median p-value = 3.31E−05, weighted mode p-value = 9.00E−04, Egger p-value = 1.00E−03) but did not remain significant throughout the leave-one-out analysis, suggesting that the relationship for this particular protein could be driven by a small number of influential variants.