In subsequent advanced AMD analyses (Source data 1), CD59 glycoprotein remained related to disease risk (OR 1.07, IVW p-value = 0.04, weighted median p-value = 9.00E−04, MR-Egger p-value = 2.00E−03, weighted mode p-value = 7.00E−03). Here, CD59 is linked to age-related macular degeneration.