Clinical scores and inflammatory markers among children and adolescents with IBD (active: mild-moderate) may be improved by MD PCDAI (p = 0.02) PUCAI (p = 0.04) Serum CRP level (p = 0.01) Fecal calprotectin (p = 0.03) Serum TNF- level (p = 0.04) Serum IL17 level (p = 0.02) Serum IL10 level (p = 0.1) Serum IL12 level (p = 0.02) Serum IL23 level (p = 0.03). Here, TNF is linked to inflammatory bowel disease.