IL33 and Increased total eosinophil count: Rag2−/−Il2rg−/− mice, which lack B, T, and NK cells, reconstituted with WT ILC2s and intranasally challenged with IL-33 and GTS-21 and exhibited reduced airway hyperreactivity (AHR) and eosinophilia compared to the mice reconstituted with α7nAChR-deficient ILC2s.