SNP variants detected in the intron region of CDH4 (rs78063755), downstream region of NTRK3-AS1 (rs57729223), the intergenic region between NTRK3-AS1 and MRPL46 (rs16941601), and the intergenic region between LINC01918 and GPR45 (rs2679891) were found to be suggestively associated with depression in the Han Chinese population in Taiwan. This evidence concerns the gene CDH4 and depressive disorder.