To sum up, the present study identifies 6 hub genes (ALDH1A1, ABL1, FOSB, PDGFRA, CCND2, PTCH1) along with two miRNAs (hsa-mir-200a, hsa-mir-429) significantly influencing multiple crucial cellular processes in endometrial cancer. The gene discussed is PDGFRA; the disease is endometrial cancer.