For example, miR-6740–3p, which interacts with CCT2, is significantly upregulated in AD (logFC = 0.38540845, p = 2.34E-16) and miR-661, which interacts with HPCAL4, NECAP1, CLTA, and GNAI2, has been observed to be involved in AD via metabolic and stress pathways (Hojati et al., 2021). Here, HPCAL4 is linked to Alzheimer disease.