Moreover, hsa-miR-145-5p, hsa-miR-378a-5p, hsa-miR-550a-3-5p, hsa-miR-369-5p, and hsa-miR-605-3p targeted migraine-related genes including COL4A1, NUFIP2, TGFBR2, MACF1, DOCK4, PNKD, and YAP1 (Gormley et al., 2016; Meng et al., 2018; de Boer et al., 2020; Khan et al., 2021; Table 3). This evidence concerns the gene TGFBR2 and migraine disorder.