Research on the anticancer effect of C. caesia rhizomes exposed the effectiveness of C. caesia extract against the hepatocarcinogen, diethylnitrosamine (DEN), by enhancing antioxidant status through free radical scavenging mechanisms resulting in attenuation of hepatic enzymes in the serum (aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and cancer marker enzyme acetylcholine esterase (AChE)) [37]. This evidence concerns the gene ACHE and cancer.