Therefore, to study the relevance of MMCC to cancer progression, we used a combination of the Flp-FRT and UAS-Gal4 binary systems (Caygill and Brand, 2016) to elicit the competitive behavior of lgl mutant cells through the induction of mycOVER GFP+ Flp-out clones at 6 days AEL, when the mutant wing disc shows evident structure aberrations (compare the wild-type and the lgl mutant discs in Supplementary Figure S1). The gene discussed is LGALS4; the disease is cancer.