CXCL1 and melanoma: Increased levels of inflammation-related mRNAs, such as C-X-C motif chemokine ligand 1, 2 and 8 (CXCL1, CXCL2 and CXCL8) mRNAs, were also identified in melanoma-derived EVs compared to those derived from primary melanocytes, which may be related to a pro-inflammatory role (Bardi et al., 2019).