MKI67 and cutaneous melanoma: According to a study on cutaneous melanoma, tumors that expressed more Ki-67 (more than 10%) were thicker than tumors that expressed lower levels of this marker.17 Another study comparing the expression of this marker in patients with and without metastasis showed that in patients with oral melanoma with metastasis to various body organs, the average Ki-67 marker was 68%, which is about 60% higher than in patients without metastasis.