Interestingly, in patients suffering SkAE we found a positive correlation of (i) I-FABP with TNF levels (r = 0.906); (ii) BMI with the levels of TIMP-1 (r = 0.786), MMP-9 (r = 0.786), LBP (r= 0.928), and EG-VGF (r = 0.808); and (iii) osteoprotegerin with IBD severity (r = 0.866), calculated as Spearman correlation coefficient. The gene discussed is TNFRSF11B; the disease is inflammatory bowel disease.